MCP server for the ClinicalTrials.gov v2 API. Search trials, retrieve study details and results, and match patients to eligible trials.
{
"mcpServers": {
"clinicaltrialsgov-mcp-server": {
"command": "bunx",
"args": [
"mcp-remote",
"https://clinicaltrials.caseyjhand.com/mcp"
]
}
}
}{
"mcpServers": {
"clinicaltrialsgov-mcp-server": {
"type": "http",
"url": "https://clinicaltrials.caseyjhand.com/mcp"
}
}
}claude mcp add --transport http clinicaltrialsgov-mcp-server https://clinicaltrials.caseyjhand.com/mcpcurl -X POST https://clinicaltrials.caseyjhand.com/mcp \
-H "Content-Type: application/json" \
-H "MCP-Protocol-Version: 2025-11-25" \
-d '{"jsonrpc":"2.0","id":1,"method":"initialize","params":{"protocolVersion":"2025-11-25","capabilities":{},"clientInfo":{"name":"curl","version":"1.0.0"}}}'Search for clinical trial studies from ClinicalTrials.gov. Supports full-text and field-specific queries, status/phase/geographic filters, pagination, sorting, and field selection. Use the fields parameter to reduce payload size — full study records are ~70KB each.
Fetch a single clinical trial study by NCT ID from ClinicalTrials.gov. Returns the full study record including protocol details, eligibility criteria, outcomes, arms, interventions, contacts, and locations.
Get total clinical trial study count from ClinicalTrials.gov matching a query, without fetching study data. Fast and lightweight. Use for quick statistics or to build breakdowns by calling multiple times with different filters (e.g., count by phase, count by status, count recruiting vs completed for a condition).
Discover valid values for ClinicalTrials.gov fields with study counts per value. Use to explore available filter options before building a search — e.g., valid OverallStatus, Phase, InterventionType, StudyType, or LeadSponsorClass values.
Discover valid field names from the ClinicalTrials.gov data model. Call this FIRST when you need to know which field names to use in `fields`, `advancedFilter`, or `sort` parameters of other tools, or as input to clinicaltrials_get_field_values. Three usage modes: pass `query` for keyword search by concept (e.g., "enrollment", "sponsor", "adverse events") returning a ranked list of matches; pass `path` for drill-down into a section by dot-notation (e.g., "protocolSection.designModule") returning its individual fields; omit both for a top-level overview of all sections. Returns canonical PascalCase identifiers like OverallStatus, EnrollmentCount, LeadSponsorName — the exact names the API accepts.
Fetch clinical trial results data from ClinicalTrials.gov for completed studies — outcome measures with statistics, adverse events, participant flow, and baseline characteristics. Only available for studies where hasResults is true. Use clinicaltrials_search_studies first to find studies with results.
Match patient demographics and conditions to eligible recruiting clinical trials. Provide age, sex, conditions, and location to find studies with matching eligibility criteria, contact information, and recruiting locations.
No tools match the current filter.
Fetch a single clinical study by NCT ID. Returns full study data as JSON.
Guides analysis of a clinical trial landscape using the ClinicalTrials.gov MCP tools. Adaptable workflow for breakdowns by status, phase, sponsor, geography, etc.
topicrequired
— Disease, condition, or research area to analyze.
focusAreas
— Comma-separated aspects to focus on, e.g.: "status, phases, sponsors, geography, timeline, interventions".